Yes, there can be plenty of benefit! Differential circuits are not only lower noise, but lower distortion due to distortion cancellation at each stage of gain, compared to single-ended circuits of otherwise similar topology. When you reduce noise or distortion, due to the masking effect of the human ear, detail is revealed.
There is also a simple method of modifying any single-ended amplifier to accept a balanced signal in the differential domain, without using a transformer and not just simply adding an XLR connector. It is also inexpensive to do.
There is also a simple method of modifying any single-ended amplifier to accept a balanced signal in the differential domain, without using a transformer and not just simply adding an XLR connector. It is also inexpensive to do.