The effects of the 5th harmonic can be increased power transformer noise, increased diode radiation and it can cause synchronous motors to have a counter-rotational force. These are all things audiophiles should be concerned about.
There are very few audiophile power conditioners that can filter this harmonics (300Hz in the US). Essentially, if you can pick up your 'conditioner' with one hand then it won't touch this issue.
Elgar made some excellent power conditioners (not offered to audiophiles; they were commercial/industrial) that trounce anything offered in the audiophile world so far. They can filter this harmonic with ease.