I have made many cables with both the FP-201 spades that use set screws, and the FP-203 spades that can be crimped, as well as with spades that need to be soldered such as Cardas GRS and CGMS spades. With the FP-203 spades I have used hand crimpers and, for the past 10 years, hydraulic crimpers to forge a virtually air-tight bond between the spade and wire. I have not heard any sonic difference that I would attribute to the type of spade or connection. My only observation is that the Furutech FP-201 and Cardas CGMS spades seem to fit on my binding posts a bit more securely and so I like those two better than most others.
IMO, the OP will be just fine with his plan to use the Furutech FP-201 spades and associated set screws to secure his wires.