Unless someone has your system, it is unlikely they could really predict an outcome. I have found a little improvement in one system using double runs of an Audioquest cable that can also be internally (single) biwired. A little better low level detail. The downside is only that the double run will cost twice as much.
Some biwire cables on the market are already double runs, such as the Analysis Plus "Bi-Oval" biwire cables.
Some biwire cables on the market are already double runs, such as the Analysis Plus "Bi-Oval" biwire cables.