The absolute best it to hard wire everything, no cable ends or connectors, even wire the speaker lead directly to the speaker wires, just support them really well.
Obviously this is not a good option for most and I do not do all of it though I might someday just to see if I can tell a difference, which I suspect will be so.
The less stuff in the chain the more pure the signal simply has to be and properly done crimp connections can be better than soldered ones, less to go through as they are basically welded together.
Rick