??? Anyone Running Active Speakers Driven By A Tube PreAmp ???

No.  I don’t know what speakers you’re using or how they’re configured.  All I’m saying is that I might choose to run a line level signal from a tube preamp to active speakers if that’s possible.  If you need a digital signal going into your speakers then why are you even asking about a tube preamp?

Go with whatever provides the sound characteristics you’re looking for.  If that’s tubes fine and if it’s solid state fine, but especially with a tube pre you should obviously pay attention to ensuring the output/input impedance characteristics are compatible.  I like active ATC speakers, but if I ever own them I’ll surely pair them with a good tube preamp.  Again, it totally depends on what sound characteristics you’re looking for.