This question is wildly subjective but that's ok.
I think the first question is what kind of speakers you are using. I've been the proud owner of a pair of Klipschorns for the past 48 years, so I can use any amp I want and I have owned many over the years.
The best set up for my system is bi-amping. I use a pair of Klein-Hummel 80 WPC channel transistor amps for the bass and I keep in rotation 10 different amps of various power and circuit configurations for the mids and highs in both tube and transistor output.
I have experienced stunning results with my 30 WPC Sony V-fet and Accuphase 30 WPC Pure class A transistor amps. My push-pull 8 WPC Eastern Electric 6BM8 tube amp offers phenomenal performance. I have realized similar results with my restored 15 WPC 1958 built Fisher 30-A tube mono blocs and my Dennis Had built tube amp that can use 7 different output tubes: the 5881, 6550, and KT88 are my favorites, again running 5 to 12 WPC.
Bottom line for me? SET at the end of the day. With the K-horns SET is simply magical!!