Hi.
I used the Iris in front of a Denafrips Pontus II and Venus II taking the USB output of a Ifi Zen Stream to I2S output. Definitely made an improvement. But, I think if you find a high quality streamer with I2S output built in, the Iris wouldn't make much difference (speculative). I now have a PS Airlens that I put into my Venus II and it sounds at least as good as the Zen Stream + Iris configuration but without all the hassles of the Zen stream and additional boxes and cables.
My two cents.