Hello Eetheredge,
Quads will work fine in your room. Just give them some space behind to breathe.
By "active", I presume you mean your room is acoustically very lively, with lots of reverberant energy. That's not necessarily a bad thing. You'll be hearing more of the speaker's power response in a lively room, and the Quads will probably have smoother power response than more conventional speakers would.
When you talk out loud in that room, how does your voice sound? How does it compare to other rooms in your house? What the room's acoustic signature does to your voice is a good indication of what it will do to a loudspeaker, and from there we can plan on what's the best approach to take.
But to get back to your original question, Quads will work quite well in your room - just don't shove 'em into the corners or up against the wall. They gotta have some breathing room.
If you aren't yet committed to the Quads, you might consider Sound Lab electrostats. They do an exceptional job in some areas that might be of particular benefit in your situation (including very smooth power response). The Millennium-3 is in the size/price ballpark of the Quad 989. Disclaimer - I own & sell Sound Labs.
Best of luck to you!
Duke