I agree with 'wire everything you can'. With one exception in my case :). My REL Carbon Limited subs run wirelessly on REL's Longbow system. Why? I had node (booming) issues with the subs in traditional (easily wired) positions. I found with the wireless, I could move the subs around to find their best positions. Turns out it was all the way to each side and asymmetrical. I have a basement with odd wall shapes. In this case, I achieved better sound by moving the subs to spots where wires were difficult at best. From Tone's review of the Carbon Limiteds:
Finally, you can connect to the Carbon wirelessly, using REL’s Longbow transmitter, featuring the same functionality and inputs as the ones on the rear panel of the Carbon. This eliminates the long cables from amplifier to subwoofer and has a range of about 45 feet
My Auralic Aries Streamer can also run wirelessly, but it is most definitely wired.