@salc trying is the only way to find out. Everything matters.
However based on my experience, I follow a simple rule as I proved over and over it works every time - start from speakers and go up the chain - speaker cables, amp power cord, interconnects into amp, etc.
Plug the amp directly into the wall outlet without power conditioner
First power cord upgrade is for the amp - 10awg minimum, best possible cord you can afford
Second is for the preamp. Then on power conditioner feeding source components, then up the chain - preamp, DAC, streamer/transport
Also, I owned 3 Pass Labs amps - X250.5, XA30.8 and X260.8 monos. The generic 14awg stock power cord included with the amp is enough to get you up and running. But…every time a good power cord made a difference on these amps in my system. Even the affordable Audience Forte F3 beats the stock cord.