Amplifier speaker integration is only hard if your speakers have a hard to drive impedance curve, and if your amplifier has a high output impedance.Of course this statement is not 100% true, which is why equipment matching is important.
An example of an exception is the Quad or Sound Lab ESL, which does not sound right if the output impedance of the amp is low. There are other examples of course (the Acoustic Research AR-1, the world's first acoustic suspension loudspeaker, is probably the best-known example as it is so famous; it was designed for an amp with a 7 ohm output impedance).