What type of speaker would sound better?

1. mid-tier 3 way with multiple lower quality drivers and parts OR

2. High end 2-way with premium crossover parts and speaker drivers. 

Either one could be a stand mount, small tower, or anything in between.

For example you listen to a well recorded symphony in a 15 X 30 living room. You have 250w @ 8ohms. You start on a mid tier 3-way and then on a high end 2-way system, which do you think would sound better?