Two useful scenarios I see for using a powered sub:
1) handle the low end with smaller monitor speakers that do not do much below 50 hz or so.
2) provide greater flexibility for dealing with room acoustics and how that affects the low end in particular. Subs might be used to cover frequencies that full range speakers are capable of handling otherwise in this case in order to be able to fine tune the bass easier than dealing with alternate speaker placement, alternate equipment, room treatments, etc. Fewer subs are well suited for this scenario in that they must perform well at the lowest frequencies in order to add value over good full range speakers
1) handle the low end with smaller monitor speakers that do not do much below 50 hz or so.
2) provide greater flexibility for dealing with room acoustics and how that affects the low end in particular. Subs might be used to cover frequencies that full range speakers are capable of handling otherwise in this case in order to be able to fine tune the bass easier than dealing with alternate speaker placement, alternate equipment, room treatments, etc. Fewer subs are well suited for this scenario in that they must perform well at the lowest frequencies in order to add value over good full range speakers