What are the best speakers for Mac MA252?

I'd say a Focal Aria 906 + a JL E110 sub.  Retail would be $2500 for both : but Focal is running a sale on closeout Dark Walnut 906's for $999.  Stands (necessary) do add about $300 though.  

Op said he wanted a sub...otherwise I would have recommended a Focal Aria 926 or 936.  Don't really need a sub with a 936 : but they're not the best choice for smaller rooms.

That's a very small room : I'd strongly advise against any Vandersteen : even the 1's need a lot of room around them to sound best.

I don't think any floor standing speaker is going to work great in that space.

I would really do a stand mount monitor in a somewhat near field set up, and supplement with a small sub.  I.e. The Focal 906 + maybe a JL Dominion D108 sub (8 inch).  The 906's are forward ported, so you don't have to worry about a rear port being to close up to a wall.  And the inverted dome tweeter has wide dispersion.  The 8" sub is plenty for that size room.  

That combo at retail will run you about $2200 if you get the Dark Walnut color 906's, which are on sale for $999.