What about 845 tubes on Wilson Sophia 3...?

Cary 845 is 50W, but to what load? What is delivered power to 4Ohms? 3 Ohms? Please check an amplifier frequency/load detailed map. Usually manufacturer will shara one with you and you will see what level of distortion and power you're dealing with before experimenting. Distortion of tubes(may reach upto 10%THD for difficult loads) is what makes sound wonderful, but far away from real recording material, if that is your goal.

you can if you don't need a full range and dynamic performance. only good for vocals and compressed recordings.

wilson impedance goes bellow 4 ohms which will result terrible distortion in these regions of the frequency/impedance plot. will this distortion sound great to ears, i don't know, but will definitely be not accurate recording material playback. any professional acoustic or recording engineer would be terrified by this decision. moreover, the unused power to the load will return back as a heat causing early tube failures.
it's one of the audiophile toys to try to drive giant speakers with small tube amp or set and try to convince that little set can drive anything.