Very small room systems and synergy

I have been trying for 20 years to put together a system for a very small (10' x 12") listening room and still haven't gotten it right.  I am currently using KEF LS50's with a NuPrime IDA8 integrated with moderate success.  I realize I really don't like metal dome tweeters and I've been drawn to class D amps.  This is probably due to my budget constraints of $2000 - $2500.  Does anyone have any input for me on this?