Vandersteen 2, 2c and 2ci have all worked great with our tube amps which are OTLs, which tend to be load sensitive. So no worries using a tube amp as long as it has enough power, which in the average room seems to be about 60 Watts or so.
Vandersteen 2ci with tube amps
What are your thoughts on tube pre and amp with the Vandersteen 2ci? I can acquire a Audio Research LS2 with a V70 from someone that is near me.