Using a shore power isolation transformer at home?

Can a shore 1:1 power isolation transformer, rated 120V/60Hz and sufficiently powerful, be used in order to make a (dedicated) AC line at home cleaner (reducing neighbor's noises)?

Is there anything special I shall take into account (as opposed to installing a "home-oriented" isolation transformer)?

If I do not want the output to be balanced (would be pointless or even harmful, as I have a servo-operated variac between the receptacle and my tube amp), what is the recommended way to earth the isolation transformer?

Thanks!