upgrade tube for SF line 2

I am new in tube amp, I just pickup a used SF line 2 a month ago. They use soviet 6922, manufacture @ 03/2000. I heard changing the tube will make a big different. Can anyone recommend some brand and model? I do some research and find siemens CCa is a of the best. however, it is hard to find and the price is high. Some body told me I can just change the two tubes in the back and leave the front four as is. that can save some money. Should I change all six to some good NOS tube (but not the best) or should I put all the money in the two that is in the back? If I change just two in the back. In the further will I get benefic by changing another four? One last question, how about bias? Do I need to re-bias them?