If your electric circuit takes a lightning strike, no fuse or protection device is going to protect it. Lightning travels for miles in air, once it attaches to the grid, it’s going to ground, through everything connected.
Unplug or ride out the storm?
In most years we have a couple of severe thunderstorms and to be safe I unplug everything. This summer is like twilight zone. Probably 15 or 20 significant electrical storms. I've been unplugging everything even though I have Furman surge protection and power conditioning. I'm confident it will work if called upon but don't want to put it to the test if I don't have to. Kind of like lifeboats on a ship. They probably work fine but you'd rather not have to test them out. The bad part (whether placebo or real) I'm convinced some of my components take anywhere from 2 hours to 2 days to really hit their stride when they've been unplugged and allowed to cool off. Just curious what everybody else does