Uneven speaker cable lengths?

I switched back to Vandersteens a while back and am trying to extract the last bit out of the setup. I have been using Cardas Clear with great success. However Clear can not be biwired, and Clear Beyond is out of my range.

Would I notice a difference if I use a 2m pair on one side and a 3m pair on the other side.

I am currently trying Clear Reflection biwired, and the biwired setup is an improvement in many ways. But the Clear is more to my liking.