You can run a good tube preamp into either tube or solid state power amps, so there’s no reason NOT to run a tube preamp if you get a good one. But power amps are a different story. I’ve had more than one friend spend Large Cash on a tube power amp solution that just didn’t work for them. BIG BUX tube amps.
I see the problem as being one of matching the tube amp to the loudspeaker. Some loudspeakers are much easier to drive than others for tube amps. I saw a recent ad of a guy selling off his beloved Marantz 8B power amp which he used to drive Altec 604E loudspeakers. That’s a well-matched choice.
But some loudspeakers are a much more difficult thing to drive and a tube amp may well not be the right choice. Most tube amps have only modest amounts of power, which also limits your choice of loudspeakers. Many who run tube amps use them to drive horn systems, which is a problem right there. Horns are flared pipes and are inherently resonant and colored, especially in the mid-range.
Today a lot of serious audiophiles are getting into multi-amplification with active crossovers, or powered loudspeaker systems like the Dutch & Dutch 8c, or some of the powered KEF systems. Systems like that have already made the amplifier choice for you.
One of my all-time favorite loudspeakers, the big Avalon systems, have extremely complex passive crossovers and don’t play well with most amplifiers. Even with a big, powerful tube amp, they probably wouldn’t do well. They don’t even like many solid state power amps. Their reputation is that they only play well with Rowland Research amps and they ain’t cheap.
Lastly, tube power amps are expensive to buy and expensive to maintain as the output tubes wear out and are costly to replace.
Get a tube preamp you like and make the power amp and speaker choices a different issue.
And of course, your budget has a lot to do with this and you didn't say anything there. My reservations about tube amps aside, one of the most magically musical systems I ever heard was a pair of late 1970's vintage KEF Calinda loudspeakers being powered by a Marantz 8B amp.
