The New Synergistic Research Purple Fuses

I received my Purple Fuse on Monday Feb 7th.  It has been playing non stop since.  I noticed my system was more harsh, it was irritating my ears.   Then I remembered I forgot to try it in the other direction.  I did so just now, but I'm not sure I can tell a difference.  Is the difference supposed to be very obvious?   If I ran it the wrong for 72 hours, does that hurt the fuse in any way?

Thanks for the response Ted.  I switched it back to the original direction because I couldn't hear a difference.   I already. have 72 hours in that direction, are you saying switch it back to the new direction I just tried today and give that 24 hours?