If you can hear differences between interconnect cables then the source is not controlling the cable.
This has been understood for the last 60 years. The history of balanced line operation goes back to the phone company, and its success was immediately taken up by the recording and broadcast industry and resulted in what was called 'hifi'.
I wish more people would get this. The 600 ohm standard eliminates cable artifacts. It is that simple. Unfortunately high end audio embraces single ended designs much more so than true balanced differential designs that support the 600 ohm standard. As a result we have cables that in some ways can act as tone controls and as a further result we have cable manufacturers who add who knows what to their cable designs to propagate this further, while taking the opportunity to charge a premium for their tone controls.
My experience with single ended designs has taught me to use very short interconnects with low capacitance to eliminate artifacts, but the sources have to be up to the task as well. Much more complicated than my balanced system that supports the 600 ohm standard, thanks to Ralph's help.