An industry expert I trust suggested AES/EBU over I2S. Which I've been using (Audience AU24SX).
Recently bought a Tubulus Argentus I2S cable, from DDC to Dac. I really like it, and will sell the Audience.
I asked Aldwin from Tubulus what the difference in the V2 Argentus was.
"Argentus V2 model has some conductors added to make it compatible with all i2s equipment."