No. To truly evaluate any changes in your system, leave everything else unchanged. The differences between components is often very subtle and these changes can easily be overwhelmed by even minute changes in speaker position. After you have thoroughly familiarized yourself with the changes wrought by the new component, then you might have to make some minor changes in speaker setup.
Speaker Placement/new component
I have a rather heated debate going on with a fellwo audio-NUT regarding if after adding a new component(amp,preamp,I.C.'s) if some experimentation with speakers placement should take place.What do you think??