Beautiful system.
Yes, probably it will make a difference. The biggest difference I have ever heard was in a digital SP/DIF cable… and it was huge… like component level. But it is component dependent. So like in all things… you have to try. Given your components I would recommend Transparent.
You discovered for yourself the difference between USB and SP/DIF. They are fundamentally different connections… it depends on your DAC and streamer. The USB transmits packets and they have to be unpacked and retimed… they added this because of PCs… SP/DIF has been around forever. On my system with a Aurender W20SE streamer ARC DAC is the two are nearly indistinguishable.