@marquis4099 The differences you usually hear have to do with how tubes and traditional class A or AB solid state amps make distortion.
Quite literally the 'sonic signature' of any amp is its 'distortion signature'.
I used the word 'traditional' as there are class D amps now that have a distortion signature much like tube amps do, and unsurprisingly, sound very similar as well- but with greater transparency owing to lower distortion overall.