Nocaster, I think that with the Guarneri's one gets a little spoilt since they do so many things right. However, in a large room I happen to think you need a large speaker, or at least one that can fill the room easily without strain. The Guarneri's are fantastic in a small-medium size room, in a large to very large room, I think more ability to move air is a requirement.
It's a simple law of physics that x number of large drivers can move more air than x number of small drivers.
It's a simple law of physics that x number of large drivers can move more air than x number of small drivers.