To me, the issue may even be a bit more complicated. While I agree with Charles that proper implementation may help to overcome the theoretical disadvantages of PSET, it is likely to be more expensive. As a result, if one does not need increased power, then SET makes the most send. However, if one DOES need increased power, then the other comparison is PSET using lower power tubes (300b, 2a3, 45) versus SET using higher power tubes (845, 211, EL34).