Agree with getting your room setup first. It will have the most impact on what you hear coming out of your system. I would then upgrade your source. Moving from the Bluesound Node N130 to an Innuos Zen Mk3 streamer and a Holo Audio Cyan 2 DAC made my speakers sound different. So much more detailed. Hearing things I didn’t before with the same setup. Changing the source had More impact for me than the preamp, amp and cables. I also play CDs and upgrading the player didn’t have as much impact as changing the streamer and DAC. Next the speakers. Suggest floor standing with your room to fill the space with sound. A good pair can work without a sub unless you need the room to shake for movies. I have a pair of Arendal 1723 towers. Finally, Make sure your amp can power the speakers you choose so they can produce the volume you want at no more than 50% volume setting, to prevent clipping. What you get will depend on your budget.
In my experience the 3 most important factors are:
1. Room setup
2. Source - most importantly for streaming
3. Speakers
Enjoy your new musical journey. It’s a fun part of this hobby. And as Hans says, enjoy the music!