You will be in for an amazing experience in upgrading to that level of speaker.
Speakers come with sound characteristics that are vastly different. Vastly! So, I recommend not considering anything other than sound quality as a first cut. If at all possible go to a city and listen to some of the major categories of speakers to see what kind of sound they have, and what you are drawn to. That kind of money really is best spent after exhaustive listening.
I would listen to Sonus Faber (musical and natural not un-totem like), B&W (huge punch with a bit of sizzle), Magico (really fast accurate and clean), Wilson (detailed and holographic), Magniplanar (ribbon, really fast and detailed). Each will be supported better by certain kinds of components. So, you are starting in the right place.
But take as much time as you can zeroing in on the sound you want. Your experience with different speakers you have now will be of value.