Absolutely. And this shouldn't be too surprising - you can roll single parts like caps and hear a difference, so why wouldn't whole different preamps sound different too?
At my home audio playground I have 3 relatively high end (not ultra-fi) preamps, 3 amps, 2 phono stages, many cartridges and SUTs. Each component has its own distinct sonic fingerprint. When I take a component to my buddy’s system - very different room & system - the sonic fingerprint follows. Cables have this too, but to a lesser degree. Different combinations of components obviously adds to the variability and complexity - some are surprise combinations that work better than expected, and others that are worse.
The so-called implications of this don’t bother me a bit - I’m not in the pursuit of "ultimate truth" like some self-important amateur philosopher. I’m seeking different and better audio experiences for my personal musical enjoyment. My experience with great-measuring darlings of the ASR crowd (Benchmark, RME) has been bad, so I don’t even care if that represents "truth" - it sounds bad to me and I don’t want it.