If you want to keep it within a budget of say $3K, then there are some great options, including:
Off-Ramp 5 driving I2S cable to Wired 4 Sound DAC2. This is a world-class sound rivalling $15-20K DACs.
Off-Ramp 5 driving S/PDIF to Metrum Octave DAC is almost as good.
The problem is getting a great DAC that ALSO has a great USB interface.
The PWD can be excellent, but needs the bridge IMO. This can be problematic too. I have customers that have abandoned the bridge to use Synchro-Mesh or Off-Ramp 5 to drive it.
USB is no cake-walk either. Dont expect to crush your CD transport with a PC and iTunes. It takes more than this. Here are my recommendations:
http://www.empiricalaudio.com/computer-audio/
http://www.empiricalaudio.com/computer-audio/recommended-systems
If you choose the right software and hardware pieces, the result can even beat the best vinyl, not just your CD transport. The important take-away from this is that the master clock, which is in the USB interface or network interface is THE MOST IMPORTANT thing in the digital audio system. This is why it sometimes makes sense to drive a USB DAC using S/PDIF and an outboard USB converter.
Steve N.
Empirical Audio