Polarity between amps

First time question and is probably a basic 101 for many. My EE tube pre amp inverts polarity, my new Consonance M400 mono blocks do not to my knowledge. Should my red speaker lead be plugged into the black negative out of the amp and also run into the black lead of the speaker and not to complicate but they are bi-wired speakers, do I also reverse the other leads at the speaker end also. Appreciate any feedback. Thanks.
Danham