installed new 4s11 canare speaker cables with double wiring to fit my recently acquired PBN speakers. I got about 30 hours on the cables and they have been all over the map so far, specially the first 25 hours. Sometime bass lacking, sometimes piercing highs, sometimes opposite. For real. The last few hours they seem to be stabilizing and I can start seeing their potential but it will take a lot longer to achieve it. So yeah, speaker cables do get better with use, not a single doubt in my mind.
Same issue as when I installed Canare 4S11. I allowed them to break in for 200 hours during which the sonics were changing all over the place. After I had given them what I thought was enough time, the highs sounded harsh and brittle. I gave up and put them in the closet.
A few years later after a major system upgrade, I tried them again due to all the good user reviews. After another 200 hours they settled in and presented a smooth top-end, very good dynamics, and a level of transparency that was an additional upgrade to my system.