I am also going to mention taking a look at some of the brands that @kennyc mentioned - Iconoclast and Zenwave. I do also use AcousticZen Hologram speaker cables as well and am impressed with their musical and open presentation.
While design is critical with cables, I have come to believe that using UPOCC copper and silver can really improve sound quality. I had some Iconclast TPC interconnects and recently compared them to their UPOCC cable (same exact design, just different copper) and the UPOCC was definitively better.
I also have recently had the opportunity to listen to a new Zenwave all UPOCC silver interconnect and it is a keeper. Dave at Zenwave is great to talk with and can guide you through his whole line at different price points. He is very focused on making great cables at different levels using the best quality cable and connectors he can.