However, as long as the BluOS control device (PC, tablet, cellphone) is on the same network, it should be able to control the BluOS2i MDC card for streaming services and NAS. So if the wifi bridge is on the same network, it should work - although, I haven't tried it.
Also, I had the HDM-2 MDC card installed in C388, and it works great too - now moved to the M12. I use it for watching music videos on YouTube, concerts, Netflix, and Bluray - essentially a 2-ch music/video experience.
The BluOS app also has an Alexa skill available for voice control using Azon Echo devices. "Alexa, ask Bluevoice to...", benefit to doing it this way is the stream isn't bit-reduced by the Echo device; instead, you get full quality/resolution of the streaming service. Have used Tidal this way, before switching to Amazon Music Ultra HD family plan. BluOS MDC supports MQA and does Tidal just fine, but the cost/value/library and ease of use with AzonUHD wins. Pretty wife can listen to country in one room, son can listen to Celtic metal (or whatever that noise is called), while I enjoy my music on the 2-ch system all simultaneously in UHD - which is brilliant. At this point, we have 3 BluOS devices; M12, C388, and a Node2i, which can be easily grouped/ungrouped spontaneously for multi-room/whole-home effect (similar to Sonos/Heos/MusicCast/etc.) all in UHD - and with access to AzonHD personal playlists (my Denon AVR w/HEOS can't do that). My impression is BluOS is a great system with awesome functionality, which adds tremendously to the value of NAD units like C388, M12 and others.