I have a similar sized room. If you have ruled out wiring problems you may want to return the speakers. It wouldn't be the first time something Italian left the factory with a problem.
I am running Yamaha NS-5000's driven by Wyred 4 Sound SX-1000R monoblocks with a Rythmik G25HP subwoofer. Bass is fine on axis.
You may want a full surround system from what you write. Get three bids from sound installers. Big rooms are trickier.