Comments on the design difference between DAC’s are spot on, R2R will have a very different sound signature vs those with newer chip designs
Are you getting confused between the old resistance ladder designs and the much later R2R technology? What DAC chip designs are newer than R2R?
I mostly listen to SACD and to me the most important thing about a DAC is that it natively handles Direct Stream Digital, which in theory means it just needs a low pass filter. Each successive bit just says shift the output level up or down one. No resistance ladder or R2R needed except when decoding Pulse Code Modulated input.