Movie Stars that can handle musical instrument well

It's an old trick to include famous actor for better commercial success. Johnny Depp plays scored few notes on the guitar pretty clean, but still think it's more for commercial success than for the benefit of the gig.

Johnny Depp has been playing guitar for years in different bands, don't know his skill level.

What about Bradley Cooper, real or movie musician?

I know that Colin Firth learned to play the guitar as a child, but later he was banned from this instrument. Instead, he was offered to learn how to play the euphonium - a bass musical wind instrument. Later he played in a rock band, but it's just not very clear on which instrument.

The Bacon brothers

Levon Helm was (he of course played Sissy Spacek’s father in Coal Miner’s daughter), Dwight Yoakam (Sling Blade), and Billy Bob Thornton is the drummer in a Pop/Rock group. Loudon Wainwright III has done some acting, as has Sting. Jeff Goldblum is a very accomplished pianist. And Jeff Bridges did a great job of playing a Country singer in Crazy Heart, and had a solo album a coupla years ago.