Aroc got a good point.
"No problems assuming your preamp can drive long interconnects."
Well, most of the preamps can't drive long runs. To handle long runs, this requires current delivery. What does our common sense say? Power amp is power amp and will deliver the current, preamp will do this hardly. You think that they can but at what cost? Now, try exactly the opposite. Try as short inerconnects as possible and use longer speaker cables. I bet you any money that the result will be better than long interconnects and short speaker cables, no matter the mono-block benefit.
Peace