I'm not knocking the Meridian 500 transport, but another thing to keep in mind is that I don't believe you can get replacement parts for that transport so it could be a paperweight. There is good synergy between Meridian components but if you look at all the big meridian forums they us Squeezeboxes feeding their DSP8000, DSP7000 speakers for the most part. I own a Meridian 568.2 and personally don't find it very musical compared to my old EAD Signature for music. My friends 508.24 CD player is a very nice unit, but even my Compli sounds more natural and refined. If you don't have a modified powersupply on the SB3's then you are missing a lot! This is a manditory upgrade in my opinion if you have full range speakers.
You might even consider getting the analog section of the SB3 modified by Bolder Audio and run it as a preamp/DAC if that is your only source.. that is suppose to be amazing plus you save $$$ on interconnects, power cords, etc..
Any way you cut it you will listen to more music with the Squeezebox than with anything else.....