Mlauren,
The amps you've used and mentioneded are all very good to excellent amps. They're very unlikely to be the source of any harshness. Ever consider adding a tubed preamp into the mix? They normally tame harshness and may solve your issue of fatigue. Good units won't sacrifice the details either. Plus, you could tailor the sound you want by the preamp as well as the tubes you use. Good luck
The amps you've used and mentioneded are all very good to excellent amps. They're very unlikely to be the source of any harshness. Ever consider adding a tubed preamp into the mix? They normally tame harshness and may solve your issue of fatigue. Good units won't sacrifice the details either. Plus, you could tailor the sound you want by the preamp as well as the tubes you use. Good luck