Long Video or Long Audio??

Definitely choose the shorter audio cable runs. You will also save $$ on cabling.

Perhaps, the use of remote control devices wil decide for you.

what home theater processor are you going to use...does it have a remote control extender jack port? the main thing about components in another room is either you don't have enough room for them and your speakers or in my case large speakers that will cause vibration of the components and degrade the whole experience...i also went under floor with pvc too keep people from standing on my cables...the tv cables would be less affected in long lengths..my cables are all at least 25 ft and it sounds great..send me more specific info as to cable brand and model and your speaker and component models...i've been into this for awhile and have got my own system where i want it...one other thing i play lps and that just doesn't go with vibration and isolation can be a bitch and expensive..send me a drawing of your room set up if u want...take care dusty akers kona hawaii