+1 Almarg
In the end it boils down to the choice of components.
Are the components high fidelity or not?
Are the components designed to give accurate high fidelity that is independent of the cables used and their length or not?
A setup that sounds different with every slightly different piece of wire is obviously NOT high fidelity - the sound is all over the place and totally dependent on extraneous factors which can never be properly controlled or determined.
In the end it boils down to the choice of components.
Are the components high fidelity or not?
Are the components designed to give accurate high fidelity that is independent of the cables used and their length or not?
A setup that sounds different with every slightly different piece of wire is obviously NOT high fidelity - the sound is all over the place and totally dependent on extraneous factors which can never be properly controlled or determined.