I can't answer that question from a strictly audio point of view, but I can tell you that I used to have a PC repair business and serviced some computers at smokers' homes. It was disgusting. At times I took PCs outside in the middle of winter just so the smell didn't nauseate me.
The most common problem I found in smokers' computers was malfunctioning RAM and CPUs - two of the most sensitive pieces in a computer. While the smoke particles didn't actually affect the parts themselves (at least not enough to cause serious errors), it fell into the mounting slots and reduced the connection. After I opened up and cleaned the innards of the PC it ran better. Audio equipment has similar characteristics of electronic boards and cables being mounted into other boards.
I wouldn't worry about the audio equipment though. What about your health?
The most common problem I found in smokers' computers was malfunctioning RAM and CPUs - two of the most sensitive pieces in a computer. While the smoke particles didn't actually affect the parts themselves (at least not enough to cause serious errors), it fell into the mounting slots and reduced the connection. After I opened up and cleaned the innards of the PC it ran better. Audio equipment has similar characteristics of electronic boards and cables being mounted into other boards.
I wouldn't worry about the audio equipment though. What about your health?