Not unless your amp is designed to accommodate them. Some amps can take both the smaller power tubes (KT77, EL34, 6L6GC, etc) and the larger ones (6550,KT88, KT90, KT120, and KT150), such as some made by Primaluna and Cary, most cannot. Check with the manufacturer of your amp or run down a copy of it's manual - that should solve your question.
