If cables can break-in, can they then wear-out?

The phenomenon of cable break-in (is it really dielectric break-in?) must be physical to the cable/dielectric/insulator/termination, therefore will extended use wear out the cable?
I do not mean metal wear from plugging in and removing, either. I am assuming permanent installation.

In my opinion it's as much our ears getting acquainted as it is break-in.